ISSN 1662-4009 (online)

ey0017.8-18 | Food for Thought | ESPEYB17

8.18. Interaction between hypothalamic-pituitary-adrenal axis genetic variation and maternal behavior in the prediction of amygdala connectivity in children

E Pozzi , CA Bousman , JG Simmons , N Vijayakumar , O Schwartz , M Seal , MBH Yap , NB Allen , SL Whittle

To read the full abstract: Neuroimage. 2019; 197:493–501. PMID: 31077842.A large body of evidence suggests that the early environment can influence the health and wellbeing in children later in life. Variability in susceptibility to environmental stimuli might be mediated by interactions between genetic variations and the environment. The hypothalamic-pituitary adrenal (HPA) axis is th...

ey0016.8-4 | New Mechanisms | ESPEYB16

8.4. Associations between adrenarcheal hormones, amygdala functional connectivity and anxiety symptoms in children

MEA Barendse , JG Simmons , ML Byrne , G Patton , L Mundy , CA Olsson , ML Seal , NB Allen , S Whittle

To read the full abstract: Psychoneuroendocrinology. 2018; 97: 156–163.Anxiety disorders are common in childhood and adolescence and the transition from childhood to adolescence seems to be a vulnerable period for the development of anxiety symptoms. This article elucidates the impact of androgens (DHEA, DHEAS and testosterone) on functional connectivity of the amygdala while ...